Polycystic ovary syndrome (PCOS) is a common endocrine disorder which affects a significant number of premenopausal women in Australia. PCOS has long-term clinical implications which can lead to decreased quality of life and psychological morbidity. A major contributing factor to this is the impact of PCOS on a woman’s fertility. However, there are a number of treatment modalities that may be used to treat PCOS-related infertility and with appropriate treatment, a woman’s prognosis with regards to PCOS-related infertility can be excellent.